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San Francisco improved to 4-0 SU and 3-1 ATS with a 24-14 Week 4 triumph over Denver as a three-point home chalk. It was the team's third double-digit victory.
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49ers 4-0 SU with Purdy; third double-digit win in Week 4.

San Francisco 49ers improved to 4-0 SU and 3-1 ATS with a 24-14 Week 4 triumph over Denver as a three-point home favorite, marking the team's third double-digit victory. The 49ers are one of three remaining unbeatens and are 16-5 SU and 13-8 ATS since the 2025 season kicked off, though they are just 3-4 SU/ATS as an underdog.

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