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Article5 things to watch in 49ers’ preseason opener vs. Titans
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There will be no Christian McCaffrey, George Kittle or Nick Bosa, who count among the 20-plus players dealing with injuries of some form or another.
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Negative signalInjury

McCaffrey sidelined for preseason opener with ongoing injury.

McCaffrey is among 20-plus 49ers players dealing with injuries and will not participate in the preseason opener against Tennessee; he is expected to miss at least another week of action.

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