From the episode

Thumb injury on the throwing side, it's going to swell. It's going to be hard for him to play through that... my minimum suspicion on this is a couple of weeks.

STACKED’s take

Negative signalInjury

Mayfield likely faces a multi-week absence due to a throwing-hand thumb injury.

Deepak Chona notes Mayfield's thumb injury on his throwing hand will likely cause swelling and difficulty playing, with a minimum suspicion of a multi-week absence pending imaging.

Baker Mayfield headshotBaker MayfieldQB · TBPlayer page — value, ADP, projections, and every insight