Yahoo Sports NFL on James Cook

ArticleTexans Place Rookie DT Kayden McDonald on IRSeptember 12, 2026

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defending NFL rushing leader RB James Cook, who ran for 116 yards and a touchdown at a piercing 6.8 Y/A against our mighty Texans defense in Week 12 last year.

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Defending rushing leader Cook faces depleted Texans DL in Week 1.

RB James Cook is the defending NFL rushing leader and will face a Texans defense depleted by four defensive linemen on injured reserve. Cook ran for 116 yards and a touchdown at 6.8 yards per attempt against the Texans defense in Week 12 last year, setting up a favorable matchup for the Bills offense in Week 1.