From the episode

if Jonathan Taylor gets hurt. I think Seth McGowan is actually a three down backup...If you have John Taylor, Seth McGowan, if you have Saquon, you can get Tank Bigsby.

STACKED’s take

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Taylor's handcuff McGowan is worth rostering in 12-14 team leagues.

The source mentions Jonathan Taylor as the Colts' lead running back and suggests that Seth McGowan is a reasonable handcuff in deeper leagues if Taylor gets injured, as McGowan would likely get the majority of the touches.

Jonathan Taylor headshotJonathan TaylorRB · INDPlayer page — value, ADP, projections, and every insight